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Table 1

Taxonomy of hazard endpoints used in the Chemical Hazard Data Commons11. DOI: https://doi.org/10.1525/elementa.422.t1

GroupingEndpoints

 
Group I human Carcinogenicity
Mutagenicity
Reproductive toxicity
Developmental toxicity
Endocrine activity 
Group II human (single exposure) Acute mammalian toxicity
Systemic toxicity/Organ effects, single exposure
Neurotoxicity, single exposure
Eye irritation
Skin irritation 
Group II* human (repeated exposures) Systemic toxicity/Organ effects, repeated exposures
Neurotoxicity, repeated exposures
Respiratory sensitization
Skin sensitization 
Ecotoxicity Acute aquatic toxicity
Chronic aquatic toxicity
Terrestrial ecotoxicity 
Physical hazard Flammability
Reactivity 
Environmental fate Persistence
Bioaccumulation
Persistent bioaccumulative toxicants (PBT)
Global warming Ozone depletion 
GroupingEndpoints

 
Group I human Carcinogenicity
Mutagenicity
Reproductive toxicity
Developmental toxicity
Endocrine activity 
Group II human (single exposure) Acute mammalian toxicity
Systemic toxicity/Organ effects, single exposure
Neurotoxicity, single exposure
Eye irritation
Skin irritation 
Group II* human (repeated exposures) Systemic toxicity/Organ effects, repeated exposures
Neurotoxicity, repeated exposures
Respiratory sensitization
Skin sensitization 
Ecotoxicity Acute aquatic toxicity
Chronic aquatic toxicity
Terrestrial ecotoxicity 
Physical hazard Flammability
Reactivity 
Environmental fate Persistence
Bioaccumulation
Persistent bioaccumulative toxicants (PBT)
Global warming Ozone depletion 
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