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Table 3.

Students’ questions for Activity 3.

Students’ questions
Why do some individuals with DS have different phenotypes if they have the same disorder? 
Do all of the genes that are triplicated in DS have an effect on an individual’s overall phenotype? 
How do genes cause certain phenotypes? 
Why does having three copies of a chromosome lead to abnormal phenotypes? 
Is Trisomy 21 the only example of a disorder caused by the presence of an extra chromosome? 
Can a person have an extra copy of chromosome 21 and be normal? 
Students’ questions
Why do some individuals with DS have different phenotypes if they have the same disorder? 
Do all of the genes that are triplicated in DS have an effect on an individual’s overall phenotype? 
How do genes cause certain phenotypes? 
Why does having three copies of a chromosome lead to abnormal phenotypes? 
Is Trisomy 21 the only example of a disorder caused by the presence of an extra chromosome? 
Can a person have an extra copy of chromosome 21 and be normal? 
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