Iran’s nuclear issue is considered one of the factors that has shaped the regional dynamic in the Arab Gulf sub-region because it is a major factor that might affect the perception of the other side players in the region, international, and regional actors. This matter represents a challenge to the security of the Gulf States. This started to change after the signing of the nuclear deal known as the “Joint Comprehensive Plan of Action” (JCPOA), but then, upon the withdrawal of the Trump administration from this agreement in May 2018, regional alignments began to be reformed. It is within this context that this article tries to answer the following question: How does the American withdrawal from the JCPOA affect the stability in the region and change the stand of the Gulf countries and other regional states? This study is based on the following hypotheses. The withdrawal of the American administration from the nuclear deal, and its imposition of a “maximum pressure” policy, represented a turning point in the vision of the region and has again cast the shadow of the Cold War over the Gulf area. The American withdrawal from the nuclear deal is an independent variable, while the regional security system and the policy of the Gulf States toward this deal is the dependent variable.

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