Arts-related science activities provide unique opportunities to engage students' strengths and motivate different types of learners (Jolly, 2014). Incorporating arts into the discussion of gene expression and microbiology introduces students to a multidisciplinary approach to STEM and provides an opportunity to explore the use of science in different fields such as design, art, and industry. In this protocol extension students create living works of art on agar plates by “painting” with E. coli that express fluorescent proteins of various colors.

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